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The PCT advantage

Sepsis is caused by an over-reactive immune response to blood-borne infection and leads to widespread inflammation.  Without timely and effective treatment, sepsis can cause tissue damage, organ failure, and death.

Procalcitonin (PCT) is a biomarker that offers advantages over other testing methods:

  • Higher specificity for bacterial infections 1-4
  • Rises within 3-6 hours after infectious challenge 5
  • Rapidly and reliably declines as septic infection resolves 4,5,6,7

PCT supports repsonsible antibiotic use

  • The ability of PCT to differentiate bacterial from viral infection allows for more appropriate administration of antibiotics
  • Monitoring PCT improves patient management and treatment

Enhance Lower Respiratory Tract Infection (LRTI) management

  • Distinguishing between bacterial and viral infections is challenging- especially in LRTI. 
  • Limitations exist with current testing procedures

BROCHURE

Download the Lumipulse® G B•R•A•H•M•S PCT brochure now to receive more information.

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References

  1. Muller B, Becker KL, Schachinger H, et al. Calcitonin precursors are reliable markers of sepsis in a medical intensive care  unit. Crit Care Med. 2000;28(4):977-983.
  2. Clec’h C, Ferriere F, Karoubi P, et al. Diagnostic and prognostic value of procalcitonin in patients with septic shock. Crit Care Med. 2004;32(5):1166-1169.
  3. Meisner M. Update on procalcitonin measurements. Ann Lab Med. 2014;34(4):263-273.
  4. Harbarth S, Holeckova K, Pittet D, Ricou B, Grau GE, Vadas L. and Interleukin-8 in Critically Ill Patients Admitted. Am J Respir Crit Care Med. 2001;164:396-402.
  5. Brunkhorst FM, Heinz U, Forycki ZF. Kinetics of procalcitonin in iatrogenic sepsis. Intensive Care Med. 1998;24(8):888-889.
  6. Ball J, Venn R. The 21st International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 20-23 March 2001. Crit Care. 2001;5(3):138-141.
  7. Soni NJ, Samson DJ, Galaydick JL, et al. Procalcitonin-guided antibiotic therapy: a systematic review and meta-analysis. J Hosp Med. 2013;8(9):530-540.

 

Reagent developed in collaboration with B•R•A•H•M•S GmbH.
B•R•A•H•M•S PCT is a registered trademark of B•R•A•H•M•S GmbH.

FDI-483  03/18